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Browsing by Author "Joseph, Lavania"
Now showing items 1-6 of 6
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Ismail, Nazir Ahmed; Omar, Shaheed Vally; Moultrie, Harry; Bhyat, Zaheda; Conradie, Francesca; Enwerem, M.; Ferreira, Hannetjie; Hughes, Jennifer; Joseph, Lavania; Kock, Yulene; Letsaolo, Vancy; Maartens, Gary; Meintjes, Graeme; Ngcamu, Dumisani; Okozi, Nana; Padanilam, Xavier; Reuter, Anja; Romero, Rodolfo; Schaaf, Simon; Te Riele, Julian; Variava, Ebrahim; Van der Meulen, Minty; Ismail, Farzana; Ndjeka, Norbert (Elsevier, 2022-04)BACKGROUND : Bedaquiline improves outcomes of patients with rifampicin-resistant and multidrug-resistant (MDR) tuberculosis; however, emerging resistance threatens this success. We did a cross-sectional and longitudinal ...
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Ismail, Nazir Ahmed; Omar, Shaheed Vally; Joseph, Lavania; Govender, Netricia; Blows, Linsay; Ismail, Farzana; Koornhof, Hendrik; Dreyer, Andries W; Kaniga, Kone; Ndjeka, Norbert (Elsevier, 2018-02)BACKGROUND : Bedaquiline (BDQ) is a novel agent approved for use in combination treatment of multi-drug resistant tuberculosis (MDR-TB).We sought to determine BDQ epidemiological cut-off values (ECVs), define and assess ...
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Ismail, Nazir Ahmed; Ismail, Farzana; Joseph, Lavania; Govender, Netricia; Blows, Linsay; Kaniga, Kone; Omar, Shaheed Vally (Nature Publishing Group, 2020-01-23)Universal drug susceptibility testing (DST) is an important requirement of the End TB Strategy. The Sensititre broth micro-dilution assay (BMD) tests multiple drugs quantitatively. We defined interpretive criteria for ...
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Kaniga, Koné; Aono, Akio; Borroni, Emanuele; Cirillo, Daniela Maria; Desmaretz, Christel; Hasan, Rumina; Joseph, Lavania; Mitarai, Satoshi; Shakoor, Sadia; Torrea, Gabriela; Ismail, Nazir Ahmed; Omar, Shaheed Vally (American Society for Microbiology, 2020-04)Drug-resistant tuberculosis persists as a major public health concern. Alongside efficacious treatments, validated and standardized drug susceptibility testing (DST) is required to improve patient care. This multicountry, ...
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Omar, Shaheed Vally; Joseph, Lavania; Halima M. Said; Ismail, Farzana; Ismail, Nabila; Gwala, Thabisile L.; Ismail, Nazir Ahmed (AOSIS Open Journals, 2019-02-21)South Africa remains challenged with a high tuberculosis burden accompanied by an increase in drug resistant cases. We assessed the use of the Illumina MiSeq, a next-generation sequencing platform for whole genome ...
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Allam, Mushal; Joseph, Lavania; Ismail, Farzana; Said, Halima; Ismail, Nazir Ahmed; Ismail, Arshad; Mtshali, Senzo; Mnyameni, Florah; Goussard, Pierre; Pekeur, Jade C.; Lourens, Adre; Omar, Shaheed Vally (American Society for Microbiology, 2018-01-18)We describe here the draft genome sequence of a Mycobacterium goodii isolate from a pediatric patient in Western Cape, South Africa. To our knowledge, this is the second reported genome of this rapidly growing nontuberculous ...
Now showing items 1-6 of 6