Meuffels-Barkas, JanineLuther-Binoir, IlseDaffue, WillemDeacon, FrancoisMitchell, Emily P.2020-11-162020-11-162020-03-26Meuffels, J., Luther-Binoir, I., Daffue, W., Deacon, F. & Mitchell, E.P., 2020, ‘Testicular disorder of sexual development with cryptorchidism, penile hypoplasia and hypospadias in a giraffe (Giraffa camelopardalis giraffa)’, Journal of the South African Veterinary Association 91(0), a1971. https://DOI.org/10.4102/jsava.v91i0.1971.1019-9128 (print)2224-9435 (online)10.4102/jsava.v91i0.1971http://hdl.handle.net/2263/77025Disorders of sexual development (DSD) in wild mammals are rarely described. A male South African giraffe (Giraffa camelopardalis giraffa) was identified with bilateral cryptorchidism. The testes were intra-abdominal, smaller and less ovoid than in normal male giraffes. The right testis was situated more cranially than the left and connected to a longer deferent duct with normal ampullae. One distended vesicular gland filled with mucoid material was identified. A short penis, situated in the perineal area, was directed caudally and presented hypospadias. Histologically, testicular hypoplasia was present; the epididymis tubules contained no spermatozoa and the deferent duct and vesicular gland were inflamed. The blood testosterone concentration was 16.27 nmol/L and oestrone sulphate concentration was 0.03 ng/mL. The aetiology of the abnormalities is unknown.en© 2020. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.CryptorchidismHypospadiasPenile abnormalityDisorders of sexual development (DSD)Giraffe (Giraffa camelopardalis)Article