Sungkapreecha, ChanitaBeily, Mark J.Kressler, JörgFocke, Walter WilhelmAndrosch, René2018-06-012018-02Sungkapreecha, C., Beily, M.J., Kressler, J. et al. 2018, 'Phase behavior of the polymer/drug system PLA/DEET : effect of PLA molar mass on subambient liquid-liquid phase separation', Thermochimica Acta, vol. 660, pp. 77-81.0040-6031 (print)1872-762X (online)10.1016/j.tca.2017.12.021http://hdl.handle.net/2263/65073The phase behavior of binary mixtures of non-crystallizable racemic poly (d, l-lactic acid) (PDLLA) and the mosquito-repellent/drug N,N-diethyl-3-methylbenzamide (DEET) was analyzed with respect to the effect of the polymer molar mass on the liquid-liquid (L–L) phase separation characteristics, by cloud-point measurements and differential scanning calorimetry. The PDLLA/DEET system shows a subambient upper critical solution temperature (UCST), with the critical temperature decreasing and critical polymer concentration increasing with decreasing molar mass of PDLLA. The obtained L–L phase separation curves were used to estimate the temperature-dependence of the interaction parameter, confirming that the enhanced miscibility of the system components in case of low molar mass PDLLA is due to increased entropy of mixing.en© 2017 Elsevier B.V. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Thermochimica Acta. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in Thermochimica Acta, vol. 660, pp. 77-81, 2018. doi : 10.1016/j.tca.2017.12.021.PLA/DEET phase diagramLiquid-liquid phase separationFlory-Huggins interaction parameterPhase equilibriaPolystyreneScaffoldFabricationDrug deliverySolvent systemsMolecular weightMicroporous membrane formationPostprint Article