Bosenberg, L.H.Thomas, P.2023-10-252023-10-252022Bosenberg, L. & Thomas, P. 2022, 'Cavernous transformation of the portal vein a rare phenomenon', South African Gastroenterology Review, vol. 20, no. 2, pp. 13-15, doi : 10.10520/ejc-medgas_v20_n2_a5.1812-165910.10520/ejc-medgas_v20_n2_a5http://hdl.handle.net/2263/93058Cavernous transformation of the portal vein is a complication of a prior portal vein thrombosis and carries a very poor prognosis. It is associated with portal hypertension, and the massive ascites that develops as a result, mimics other clinical conditions that may puzzle physicians. Elevated levels of Ca-125 is often seen in patients with associated underlying chronic liver disease, which in turn may lead to a wild goose chase for ovarian carcinoma. Portal vein thrombosis in HIV-positive patients, most likely as a result of HIV-associated thrombosis, must be considered in all HIV patients who present with features of portal hypertension and ascites.en© In House Publications.Portal vein thrombosisCavernous transformation of portal veinCa-125 levelsHIV-associated thrombosisHuman immunodeficiency virus (HIV)SDG-03: Good health and well-beingArticle