Makgato, Seshibe StanfordChirwa, Evans M.N.2023-05-082023-05-082022-08-29Makgato, S.; Nkhalambayausi-Chirwa, E. An Evaluation of the Kinetic Properties Controlling the Combined Chemical and Biological Treatment of Toxic Recalcitrant Organic Compounds from Aqueous Solution. Catalysts 2022, 12, 965. https://DOI.org/10.3390/catal12090965.2073-4344 (online)10.3390/catal12090965http://hdl.handle.net/2263/90597Due to their high toxicity, propensity for cancer, teratogenicity, mutagenicity, and genotoxicity, hazardous water-soluble phenolic compounds must be controlled immediately. In this study, a model was created to simulate the degradation of harmful recalcitrant organic compounds in a combined chemical and biological treatment system. The parameter estimations with inhibition coefficient (Haldane model) and without inhibition coefficient (Michaelis-Menten model) were assessed over a wide range of initial concentrations using the Monod-like model. The kinetic parameters were optimized using AQUASIM 2.0 software. At a 50 mg L1 feed concentration of 4-chlorophenol, removal efficiencies of more than 98% were attained under these circumstances. The primary kinetic parameters were identified and their values models were validated using the fitted parameter values that reached a good degree of agreement (R2 = 0.998). We may better comprehend and make use of the complex phenolic compounds’ biodegradation processes, such as progress optimization and scale-up, by understanding the mechanisms of substrate interaction and the new kinetic models that have been provided in this work.en© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.KineticsChemical reactorBiodegradationToxic recalcitrantAqueous solutionArticle