Stoesser, NicoleSheppard, Anna E.Peirano, GiseleSebra, RobertLynch, TarahAnson, LukeKasarskis, AndrewMotyl, Mary R.Crook, Derrick W.Pitout, Johann D.D.2016-06-242016-06-242016-08Stoesser, N, Sheppard, AE, Peirano, G, Sebra, R, Lynch, T, Anson, L, Kasarskis, A, Motyl, MR, Crook, DW & Pitout, JDD 2016, 'First report of blaIMP-14 on a plasmid harboring multiple drug resistance genes in Escherichia coli sequence type 131', Antimicrobial Agents and Chemotherapy, vol. 60, no. 8, pp. 5068-5071.0066-4804 (print)1098-6596 (online)10.1128/AAC.00840-16http://hdl.handle.net/2263/53392The blaIMP-14 carbapenem resistance gene has largely previously been observed in Pseudomonas aeruginosa and Acinetobacter spp. As part of global surveillance and sequencing of carbapenem-resistant E. coli, we identified an ST131 strain harboring blaIMP-14 within a class 1 integron, itself nested within a ~54kb multi-drug resistance region on an epidemic IncA/C2 plasmid. The emergence of blaIMP-14 in this context in the ST131 lineage is of potential clinical concern.en© 2016 Stoesser et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.Pseudomonas aeruginosaAcinetobacter spp.Global surveillanceFirst report of blaIMP-14 on a plasmid harboring multiple drug resistance genes in Escherichia coli sequence type 131Article