Perez-de-Oliveira, Maria EduardaRobinson, LiamAssuncao Junior, Jose Narciso RosaAbrahao, Aline CorreaRomanach, Mario JosePenafort, Paulo Victor MendesDa Silva, Luan CesarSantos-Silva, Alan RogerLopes, Marcio AjudarteVan Heerden, Willem Francois PetrusVargas, Pablo Agustin2023-02-022022-12Pérez-de-Oliveira, M.E., Robinson, L., Assunção Júnior, J.N.R. et al. 2022, 'Tongue hamartomas in pediatric patients: an international case series and literature review', Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, vol. 134, no. 6, pp. 739-748, doi : 10.1016/j.oooo.2022.06.009.2212-4403 (print)2212-4411 (online)10.1016/j.oooo.2022.06.009https://repository.up.ac.za/handle/2263/89099This study reports 9 additional tongue hamartomas in children paired with a literature review. A retrospective analysis was performed from 3 Oral Pathology laboratories. Additionally, a literature review was conducted through 5 electronic databases and gray literature. A total of 9 cases were identified in the retrospective analysis. Females outnumbered males with a ratio of 1.25:1. The age of presentation ranged from 2 weeks to 7 years. The posterior dorsum tongue was the most affected subsite (n = 4). One case was seen in a patient with oro-facial-digital syndrome, 2 cases in patients with cleft palates, and one case with an encephalocele. The most common predominant component was salivary gland tissue (n = 4). A literature search included 79 pediatric patients presenting with 95 tongue hamartomas. A slight female (n = 47) predilection was observed, with ages varying from 15 hours to 19 years. The posterior tongue dorsum (n = 31) was the most affected site. Seven cases were seen in association with syndromes. The most common predominant component was smooth muscle (n = 35). Although hamartomas are rare in the oral cavity, they should be considered in the differential diagnosis of masses involving the posterior tongue dorsum in children.en© 2022 Elsevier Inc. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, vol. 134, no. 6, pp. 739-748, 2022, doi : 10.1016/j.oooo.2022.06.009.HamartomaPediatric patientsOral cavityPosterior tonguePostprint Article