Van Amstel, S.R.Oberem, P.T.Didomenico, M.Kirkpatrick, R.D.Mathee, J.Bigalke, R.D.2014-10-162014-10-1620141988Van Amstel, SR, Oberem, PT, Didomenico, M, Kirkpatrick, RD & Mathee, J 1988, 'The presence of endotoxin activity in cases of experimentally-induced heartwater in sheep', Onderstepoort Journal of Veterinary Research, vol. 55, no. 4, pp. 217-220.0330-2465http://hdl.handle.net/2263/42391The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.The presence of endotoxin was examined in 5 sheep with experimentally-induced heartwater. Two peaks in endotoxin levels were recorded in 4 out of the 5 sheep during the acute stage of the disease. The 1st peak coincided with or occurred shortly after the febrile reaction (over 40 °C). The 2nd peak occurred 3-5 days after the 1st, and in 2 sheep this 2nd elevation in endotoxin levels was associated with severe clinical signs (rapid and laboured breathing, cyanosis and recumbency), and 1 of the 2 sheep died on the day of the 2nd elevation. Both endotoxin peaks were of short duration and levels had decreased in the 24-h follow-up samples.en©ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Dept. of Library Services (digital).Veterinary medicineVeterinary medicine -- South AfricaArticle