Malherbe, P.J.Karayiorgou, M.Ehlers, ReneRoos, J.L. (Johannes Louw)2017-03-072017-05Malherbe, PJ, Karayiorgou, M, Ehlers, R & Roos, JL 2017, 'Increased risk of suicide in schizophrenia patients with linkage to chromosome 13q', Psychiatry Research, vol. 251, pp. 34-35.0165-1781 (print)1872-7123 (online)10.1016/j.psychres.2017.02.008http://hdl.handle.net/2263/59286We link schizophrenia in families from the genetically isolated South African Afrikaner population to chromosome 13q (n =51), 1p (n =23) and combined 13q & 1p (n =18). Patients with linkages to chromosome 13q were 4.16 times more likely to meet diagnostic criteria for schizoaffective disorder compared to patients with linkage to 1p. A third of patients with linkage to both 13q & 1p met diagnostic criteria for SAD. There was a significant positive relationship between suicidality and a diagnosis of schizoaffective disorder. Identifying linkage to chromosome 13q may be informative in identifying suicide risk early and prevent morbidity and mortality in schizophrenia patients.en© 2017 Elsevier B.V. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Psychiatry Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in Psychiatry Research, vol. 251, pp. 34-35, 2017. doi : 10.1016/j.psychres.2017.02.008.Schizoaffective disorderLinkage to chromosome 13qSuicideSchizophrenia (SCZ)Postprint Article