Okpani, Arnold IkedichiBarker, StephenLockhart, KarenGrant, JenniferDelgado-Ron, Jorge AndresZungu, MuzimkhuluNaicker, NishaEhrlich, RodneyYassi, Annalee2023-07-262023-07-262022-09Okpani, A.I., Barker, S., Lockhart, K. et al. 2022, 'A mixed-methods study of risk factors and experiences of health care workers tested for the novel Coronavirus in Canada', Journal of Occupational and Environmental Medicine, vol. 64, no. 9, pp. E559-e566, doi : 10.1097/IOM.0000000000002614.1076-2752 (print)1536-5948 (online)10.1097/IOM.0000000000002614http://hdl.handle.net/2263/91639OBJECTIVE : The aims of this study were to investigate occupational and non–work-related risk factors of coronavirus disease 2019 among health care workers (HCWs) in Vancouver Coastal Health, British Columbia, Canada, and to examine how HCWs described their experiences. METHODS : This was a matched case-control study using data from online and phone questionnaires with optional open-ended questions completed by HCWs who sought severe acute respiratory syndrome coronavirus 2 testing between March 2020 and March 2021. Conditional logistic regression and thematic analysis were utilized. RESULTS : Providing direct care to coronavirus disease 2019 patients during the intermediate cohort period (adjusted odds ratio, 1.90; 95% confidence interval, 1.04 to 3.46) and community exposure to a known case in the late cohort period (adjusted odds ratio, 3.595%; confidence interval, 1.86 to 6.83) were associated with higher infection odds. Suboptimal communication, mental stress, and situations perceived as unsafe were common sources of dissatisfaction. CONCLUSIONS : Varying levels of risk between occupational groups call for wider targeting of infection prevention measures. Strategies for mitigating community exposure and supporting HCW resilience are required.en© 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on be- half of the American College of Occupational and Environmental Medicine. This is an open access article distributed under the Creative Commons Attribu- tion License 4.0 (CCBY).Healthcare workers (HCW)COVID-19 pandemicCoronavirus disease 2019 (COVID-19)EpidemiologyHealth personnelInfectionsOccupational healthWorkplaceSDG-03: Good health and well-beingArticle