Mayaphi, Simnikiwe HoratiousVan Zyl, Walda B.Sono, TinahLoots, Donovan P.Taylor, Maureen B.2016-02-252016-02-252015Mayaphi, S, Van Zyl, W, Sono, T, Loots, D & Taylor, M 2015, 'Hand-foot-and-mouth disease caused by coxsackievirus A6 in a patient infected with HIV', Southern African Journal of Infectious Diseases, 30, no. 2, pp. 67-69.2312-0053 (print)http://hdl.handle.net/2263/51552Hand, foot and mouth disease (HFMD) is common in children ≤ 5 years of age, and is mainly caused by enterovirus 71 and coxsackievirus A16 (CVA6). A 12-year-old boy on treatment for human immunodeficiency virus (HIV) presented to an HIV clinic with fever and a rash on the palms and soles. The syphilis test were negative. Enterovirus was identified from a stool sample by PCR and characterised as as coxsackievirus A6(CVA6). The patient completely recovered a week later. CVA6 has recently been associated with HFMD. This case highlights the significance of the laboratory confirmation of suspected HFMD cases aand phylogenetic analysis of the identified virus.en© SAJIDRashHand, foot and mouth disease (HFMD)Human immunodeficiency virus (HIV)Coxsackievirus A6 (CVA6)Enterovirus 71 ( EV71 )Article