Dias, Stephanie CharmainePheiffer, CarmenAbrahams, YoonusRheeder, PaulAdam, Sumaiya2019-01-152019-01-152018-09-26Dias, S., Pheiffer, C., Abrahams, Y. et al. 2018, 'Molecular biomarkers for gestational diabetes mellitus', International Journal of Molecular Sciences, vol. 19, no. 10, art. 2926, pp. 1-27.1422-0067 (online)10.3390/ijms19102926http://hdl.handle.net/2263/68142Gestational diabetes mellitus (GDM) is a growing public health problem worldwide. The condition is associated with perinatal complications and an increased risk for future metabolic disease in both mothers and their offspring. In recent years, molecular biomarkers received considerable interest as screening tools for GDM. The purpose of this review is to provide an overview of the current status of single-nucleotide polymorphisms (SNPs), DNA methylation, and microRNAs as biomarkers for GDM. PubMed, Scopus, and Web of Science were searched for articles published between January 1990 and August 2018. The search terms included “gestational diabetes mellitus”, “blood”, “single-nucleotide polymorphism (SNP)”, “DNA methylation”, and “microRNAs”, including corresponding synonyms and associated terms for each word. This review updates current knowledge of the candidacy of these molecular biomarkers for GDM with recommendations for future research avenues.en© 2018 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.Molecular biomarkersDNA methylationMicroRNAsGenetic and epigenetic markersGestational diabetes mellitus (GDM)Single-nucleotide polymorphism (SNP)Article