Matlala, HumphreyNel, HanneliePretorius, Jan-Harm C.2025-07-102025-07-102025-06Matlala H, Nel H, Pretorius JHC. The strategic role of the enterprise portfolio management office in enabling the alignment and prioritisation of projects and programmes for organisational strategy execution. Journal of the South African Institution of Civil Engineering 2025:67(2), Art. #1702, 11 pages. http://dx.doi.org/10.17159/2309-8775/2025/v67n2a22.1021-2020 (online)10.17159/2309-8775/2025/v67n2a2http://hdl.handle.net/2263/103272Organisations continue to face challenges in aligning and prioritising projects and programmes with strategic execution, and research shows that there is a need for organisations to develop a process that could assist them in achieving this. Using a survey study and literature, this study developed a conceptual model illustrating an ideal framework for aligning projects and programmes with organisational strategy execution. The model also proposes the optimal positioning of the enterprise portfolio management office (EPMO) within the organisational value chain to facilitate effective strategy execution and benefit management.enThe Journal of the South African Institution of Civil Engineering, which is distributed internationally, is a peer-reviewed, open-access journal licensed under a Creative Commons Attribution Licence (CC BY-NC-ND).Project managementStrategic managementOrganisational changeEnterprise portfolio management office (EPMO)Benefits realisation management (BRM)Article