Ramaotsoa, Gakanego ValerieStrydom, IanPanayides, Jenny-LeeRiley, Darren Lyall2026-01-162026-01-162025-06Ramaotsoa, G.V., Strydom, I., Panayides, J.L. et al. 2025, 'Immobilized tetrakis(triphenylphosphine)palladium(0) for Suzuki-Miyaura coupling reactions under flow conditions', Reaction Chemistry & Engineering, vol. 10, no. 6, pp. 1429-1429, doi : 10.1039/d5re90015h.2058-9883 (online)10.1039/c8re00235ehttp://hdl.handle.net/2263/107377An immobilized triphenylphosphine scaffold was prepared by precipitation polymerization and functionalized to afford a cost-effective source of solid-supported tetrakis(triphenylphosphine)palladium(0). The catalyst was characterised and used to perform biphasic Suzuki–Miyaura cross-coupling reactions using a packed-bed reactor under flow conditions. The approach afforded comparable yields to those obtained under batch conditions with a single pass through the packed-bed reactor (1 h vs. 18 h). The use of a recycling system was investigated on a model reaction and found to afford close to quantitative conversion within 3 hours.en© The Royal Society of Chemistry 2025.Precipitation polymerizationCost-effective sourceCatalystFlow conditionsArticle