Mitchell, D.T.Le Roux, P.L.Du Toit, P.J.2017-03-282017-03-2820171946Mitchell, DT & Le Roux, PL 1946, 'Further investigations into immunization of cattle against rinderpest’, Onderstepoort Journal of Veterinary Science and Animal Industry, vol. 21, no. 1, pp. 7-16.0330-2465http://hdl.handle.net/2263/59555The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.1. Kabete goat virus was not transmitted from reacting to susceptible cattle under conditions of close contact. 2. A single doubtful transmission was recorded under conditions of open grazing. 3. A febrile condition of unknown aetiology transmissible from cattle to goats was encountered. 4. Urine from reacting animals was non-infective, but faeces in one out of two cases was infective by drenching. 5. Immunity produced by a single injection of formal-glycerine spleen-vaccine had completely disappeared after 8 months. 6. Immunity produced by triple vaccination with formal-saline vaccine had diminished considerably after 8 months. 7. Triple vaccination followed by a single injection of formal-glycerine spleen vaccine 9 months later produced an immunity which persisted for at least 20 months. 8. The rapid production of immunity induced by a single injection of formal-glycerine spleen-vaccine could be used to control the reaction to K.G.V. An interval of 7 days between vaccine and virus appeared to be the optimum. 9. Spleen-vaccine prepared from cattle reacting to K.G.V. has an inferior antigenic potency. 10. The reaction produced by K.G.V. in grade cattle (British breeds of cattle x Zebu) are severe but usually non-fatal. A durable immunity follows the reaction.en© 1946 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © 2017 University of Pretoria. Dept. of Library Services (digital).Veterinary medicineVeterinary medicine -- South AfricaArticle