Retter, EdnaBenn, Carol-AnnMaske, ChristopherRapoport, Bernardo Leon2023-05-082023-05-082022-02-07Retter, E., Benn, C.-A., Maske, C. et al. 2022, 'A case report of post-radiotherapy c-MYC-positive angiosarcoma of the breast', Case Reports in Oncology, vol. 15, no. 1, 62-70, doi : 10.1159/000521069.1662-6575 (online)10.1159/000521069http://hdl.handle.net/2263/90596Angiosarcoma of the breast is an unusual malignancy and carries a poor prognosis, with a 5-year overall survival rate ranging from 27 to 48%. Radiotherapy-induced angiosarcoma (RIAS) of the breast is very uncommon, with an estimated incidence of 1 in 1,000 cases of breasts treated with radiotherapy for breast cancer. The increase in radiotherapy usage may lead to an increased incidence of RIAS. A case presentation of a 67-year-old patient with tubular adenocarcinoma of the left breast who developed c-MYC-positive RIAS of the breast is presented. The patient was successfully treated with surgery. We presented a classic case of c-MYC RIAS. c-MYC was reported to be positive in RIAS and other types of angiosarcomas. Clinical examination and early detection of RIAS breast angiosarcoma is vital to improving outcomes in these patients.en© 2022 The Author(s). This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC).Breast angiosarcomaMYC positivePost-radiotherapyRadiotherapy-induced angiosarcoma (RIAS)Article