Hellferscee, OrienkaTreurnicht, Florette K.Tempia, StefanoVariava, EbrahimDawood, HalimaKahn, KathleenCohen, Adam L.Pretorius, Marthi AndréaCohen, CherylMadhi, Shabir A.Venter, Marietjie2018-01-242018-01-242017-04Hellferscee O, Treurnicht FK, Tempia S, et al. Enterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009–2011. Influenza Other Respi Viruses. 2017;11:211–219. https://DOI.org/10.1111/irv.12444,1750-2640 (print)1750-2659 (online)10.1111/irv.12444http://hdl.handle.net/2263/63700BACKGROUND : Human enteroviruses (EV) have been associated with severe acute respiratory illness (SARI) in South Africa. OBJECTIVES : We aimed to describe the molecular epidemiology of EV serotypes among patients hospitalized with SARI during 2009-2011. PATIENTS/METHODS : Study samples from patients were tested for the presence of enterovirus using a polymerase chain reaction assay. RESULTS : 8.2% (842/10 260) of SARI cases tested positive for enterovirus; 16% (7/45) were species EV-A, 44% (20/45) EV-B, 18% (8/45) EV-C and 22% (10/45) EV-D. Seventeen different EV serotypes were identified within EV-A to EV-D, of which EV-D68 (22%; 10/45) and Echovirus 3 (11%; 5/45) were the most prevalent. CONCLUSIONS : EV-D68 should be monitored in South Africa to assess the emergence of highly pathogenic strains.en© 2017 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.EnterovirusEV-D68PneumoniaSouth Africa (SA)Human enterovirus (HEV)Severe acute respiratory illness (SARI)Article