Liebenberg, A.Du Toit, J.T.Boomker, Jacob Diederik Frederik2012-12-122012-12-1220112003Knobel, DL, Liebenberg, A & Du Toit, JT 2003, 'Seroconversion in captive African wild dogs (Lycaon pictus) following administration of a chicken head bait/SAG-2 oral rabies vaccine combination'. Onderstepoort Journal of Veterinary Research, vol. 70, no. 1, pp. 73-77.0030-24656602518021O-7057-20140000-0002-0425-3799http://hdl.handle.net/2263/20692The articles have been scanned with a HP Scanjet 8300; 600dpi, saved in TIFF format. Adobe Acrobat v.9 was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.This study determined the proportion of captive juvenile and adult African wild dogs (Lycaon pictus) that developed protective titres of rabies neutralising antibodies following ingestion of a chicken head bait/SAG-2 oral rabies vaccine combination. A single chicken head containing 1.8 ml of SAG-2 vaccine (10⁸˙⁰ TCID₅₀/ml) in a plastic blister was fed to each of eight adult and three juvenile wild dogs. Bait ingestion resulted in a significant rise in serum neutralising antibody titres. Overall seroconversion rate was eight out of 11 (72.7 %), and all the puppies and five out of eight (62.5 %) adults showed potentially protective levels of antibodies on day 31. The mean post-vaccination neutralising antibody titre was within the range reported to be protective against challenge with virulent rabies virus in other species.en© ARC-Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © University of Pretoria. Dept of Library Services (digital).Veterinary medicineLycaon pictusOral vaccinationRabiesSAG-2Veterinary medicine -- South AfricaSeroconversion in captive African wild dogs (Lycaon pictus) following administration of a chicken head bait/SAG-2 oral rabies vaccine combinationArticle