Steyn, Nicolene2023-05-182023-05-182023-09Steyn, N. 2023, 'Ketamine: friend or foe?', Journal of Clinical Pathology, vol. 76, pp. 581, doi: 10.1136/jclinpath-2021-207586.0021-9746 (print)1472-4146 (online)10.1136/jclinpath-2021-207586http://hdl.handle.net/2263/90738Ketamine, a dissociative anaesthetic drug, acts on the central nervous system (CNS) primarily through antagonism of the n-methyl-d-aspartate (NMDA) receptor. Methods of administration include intravenous, intramuscular, snorting and smoking. Intranasal use, which has a very rapid onset of action, is common among recreational users.en© Author(s) (or their employer(s)) 2023. No commercial re-use.KetamineDissociative anaesthetic drugCentral nervous system (CNS)N-methyl-d-aspartate (NMDA)Health sciences articles SDG-03SDG-03: Good health and well-beingPostprint Article