Ker, James A.Outhoff, Kim2021-08-032021-08-032020-08Kera, J. A. and Outhoff, K. 2020, 'Burning Issues in the Prevention of Heart Failure', Journal of Endocrinology, Metabolism and Diabetes in South Africa, vol. 25, no.2, pp. 46–48.1608-9677 (print)2220-1009 (online)http://hdl.handle.net/2263/81118Republished with permission: South African Family Practice 2019;61(4):11-12.Chronic heart failure is common, debilitating, and often the culmination of pervasive cardiovascular insults that systematically undermine the heart’s circulatory capacity and invoke counterproductive neuro-hormonal compensatory changes. Prevention of chronic heart failure therefore requires minimising the impact of traditional cardiovascular risk factors with incisive treatment of hypertension and type 2 diabetes mellitus (T2DM) and prompt lifestyle interventions for smoking, lack of exercise, obesity and hypercholesterolemia. This review is narrative, with selected emphasis on major studies, rather than structured on a specific clinical question, and should be read as such.en© 2020 The Author(s). Open Access article distributed under the terms of the Creative Commons License [CC BY-NC-ND 4.0].Chronic heart failurePreventionCardio-protectionHypertensionType 2 diabetes mellitus (T2DM)Article