Soin, NavneetFishlock, Sam J.Kelsey, ColinSmith, Suzanne2021-05-132021-05-132021-03Soin, N.; Fishlock, S.J.; Kelsey, C.; Smith, S. Triboelectric Effect Enabled Self-Powered, Point-of-Care Diagnostics: Opportunities for Developing ASSURED and REASSURED Devices. Micromachines 2021, 12, 337. https://doi.org/10.3390/mi12030337.2072-666X (online)10.3390/mi12030337http://hdl.handle.net/2263/79872The use of rapid point-of-care (PoC) diagnostics in conjunction with physiological signal monitoring has seen tremendous progress in their availability and uptake, particularly in low- and middle-income countries (LMICs). However, to truly overcome infrastructural and resource constraints, there is an urgent need for self-powered devices which can enable on-demand and/or continuous monitoring of patients. The past decade has seen the rapid rise of triboelectric nanogenerators (TENGs) as the choice for high-efficiency energy harvesting for developing self-powered systems as well as for use as sensors. This review provides an overview of the current state of the art of such wearable sensors and end-to-end solutions for physiological and biomarker monitoring. We further discuss the current constraints and bottlenecks of these devices and systems and provide an outlook on the development of TENG-enabled PoC/monitoring devices that could eventually meet criteria formulated specifically for use in LMICs.en© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).Point-of-care (POC)ASSURED devicesREASSURED devicesPoint-of-care devicesEnergy harvestingSelf-poweredTriboelectric nanogeneratorsArticle