Ramonaheng, KamoBanda, KaluziQebetu, MilaniGoorhoo, PryaskaLegodi, KhomotsoMasogo, TshegofatsoSeebarruth, YashnaMdanda, SiphoSibiya, SandileMzizi, YonwabaDavis, CindySmith, LianiNdlovu, HonestKabunda, JosephMaes, AlexVan de Wiele, ChristopheAl-Ibraheem, AkramSathekge, Mike Machaba2026-02-092026-02-092026-01Ramonaheng, K., Banda, K., Qebetu, M. et al. 2026, 'Clinical image-based dosimetry of Actinium-225 in targeted alpha therapy', Cancers, vol. 18, no. 2, art. 321, pp. 1-35, doi : 10.3390/cancers18020321.2072-6694 (online)10.3390/cancers18020321http://hdl.handle.net/2263/107982DATA AVAILABILITY STATEMENT : All supporting data are included in the manuscript.Please read abstract in the article.en© 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.DosimetryDosimetry workflowActinium-225 SPECT imagingActinium-225 targeted alpha therapyQuantitative SPECT/CTRBE-weighted doseTargeted alpha therapy (TAT)Single-photon emission computed tomography/computed tomography (SPECT/CT)Clinical image-based dosimetry of Actinium-225 in targeted alpha therapyArticle