Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein-host ACE2 binding

Invernizzi, LukeMoyo, PhanankosiCassel, JoelIsaacs, Freddie J.Salvino, Joseph M.Montaner, Luis J.Tietjen, IanMaharaj, Vinesh J.2023-05-262023-05-262022-04Invernizzi, L., Moyo, P., Cassel, J. et al. Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein–host ACE2 binding. Analytical and Bioanalytical Chemistry 414, 3971–3985 (2022). https://doi.org/10.1007/s00216-022-04041-3.1618-2642 (print)1618-2650 (online)10.1007/s00216-022-04041-3http://hdl.handle.net/2263/90814Please read abstract in the article.en© Springer-Verlag GmbH Germany, part of Springer Nature 2022. The original publication is available at : http://link.springer.com/journal/216.COVID-19 pandemicSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Gunnera perpensaUPLC-IMS-HRMSAntiviral treatmentPunicalinPunicalaginUse of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein-host ACE2 bindingPostprint Article