Makhanya, Khanyisani MhlanganoBhamjee, MuaazMartinson, NeilConnell, Simon2026-04-162026-04-162026-07Makhanya, K.M., Bhamjee, M., Martinson, N. & Connell, S. 2026, 'Assessment and characterization of the impact of pulmonary pathology on flow-induced acoustics using computational fluid dynamics', Biomedical Signal Processing and Control, vol. 120, art. 110018, pp. 1-14, doi : 10.1016/j.bspc.2026.110018.1746-8094 (print)1746-8108 (online)10.1016/j.bspc.2026.110018http://hdl.handle.net/2263/109619DATA AVAILABILITY : The data that has been used is confidential.Please read abstract in the article. HIGHLIGHTS • Novel CFD approach to analysis of cough acoustics for pulmonary disease assessment • Studied Healthy lungs, pneumonia, bronchiectasis and cavitary tuberculosis • Method validated against 22 patient recordings with distinct clinical diagnoses • Model correlations with recordings advance understanding of respiratory acoustics • Potential to generate synthetic data to train AI model for telemedicine diagnosesen© 2026 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).Computational fluid dynamics (CFD)ExhalationFluid-flowPulmonary diseaseSound pressure levelVocalizationAero-acousticsArticle