Le Roux, J.M.W.Alexander, R.A.Clark, R.Louw, J.G.De Kock, V.E.2016-09-302016-09-3020161959Le Roux, JMW 1959, 'The histopathology of Wesselsbron disease in sheep', Onderstepoort Journal of Veterinary Research, vol. 28, no. 2, pp. 237-243.0330-2465http://hdl.handle.net/2263/57066The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.1. The histopathology of Wesselsbron disease is described. The lesions are mainly confined to the liver. This organ shows fatty infiltration, bile pigmentation, necrobiosis of the liver cells and infiltration of lymphocytes and neutrophils. The histological picture tends to be variable and the lesions in experimentally infected cases are of a much milder degree compared to those observed in natural cases. 2. Immunisation of pregnant ewes produces meningo-encephalitis in the foetuses. 3. The differential diagnosis is discussed and it is suggested that enzootic icterus probably played a role during the 1957 outbreak of Wesselsbron disease.en© 1959 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © 2016 University of Pretoria. Dept. of Library Services (digital).Veterinary medicineVeterinary medicine -- South AfricaSheep -- DiseasesArticle