Wheeler, N.Steel, Helen CarolynSetlai, Botle PreciousMeintjes, F.Mokoena, Taole2022-08-302022-08-302021-03N. Wheeler, H.C. Steel, B.D.P. Setlai, F. Meintjes, T. Mokoena, Human immunodeficiency virus infection is associated with a differential increase in cytokine response and increased risk of perforation in acute appendicitis, British Journal of Surgery, Volume 108, Issue 5, May 2021, Pages 463–468, https://doi.org/10.1093/bjs/znaa170.0007-1323 (print)1365-2168 (online)10.1093/bjs/znaa170https://repository.up.ac.za/handle/2263/86985This article is based on the MMed (Surg) thesis of N.W. for the University of Pretoria.No abstract available.en© The Author(s) 2021. Published by Oxford University Press on behalf of BJS Society Ltd. All rights reserved. This is the pre-peer reviewed version of the following article : Human immunodeficiency virus infection is associated with a differential increase in cytokine response and increased risk of perforation in acute appendicitis, British Journal of Surgery, Volume 108, Issue 5, May 2021, Pages 463–468, https://doi.org/10.1093/bjs/znaa170. The definite version is available at : https://academic.oup.com/bjs.AppendicitisHuman immunodeficiency virus (HIV)HIV‐infectionCytokinesAnti-inflammatory agentsPeritoneal fluidHIV seropositivityHuman immunodeficiency virus infection is associated with a differential increase in cytokine response and increased risk of perforation in acute appendicitisPostprint Article