Rollin, Halina B.Nogueira, ClaudinaOlutola, Bukola GaniyatChanna, KalavatiOdland, Jon Oyvind2019-05-202019-05-202018-07-15Röllin, H.B., Nogueira, C., Olutola, B. et al. 2018, 'Prenatal exposure to aluminum and status of selected essential trace elements in rural South African women at delivery', International Journal of Environmental Research and Public Health, vol. 15, no. 7, art. 1494, pp. 1-16.1660-4601 (online)10.3390/ijerph15071494http://hdl.handle.net/2263/69172This study sought to evaluate the in utero exposure to aluminum and status of selected trace elements in South African women at delivery since aluminum is known to be toxic in all developmental stages even at low concentrations. Serum aluminum was negatively correlated with aluminum in urine, both uncorrected and corrected for creatinine, which suggests the retention of aluminum in body stores. Serum copper and zinc levels were found to be high in this study population. Serum copper levels were negatively correlated with aluminum in serum ( =0.095; p = 0.05). There was a marginal negative correlation between aluminum levels in serum and manganese levels in whole blood ( = 0.087; p = 0.08). Copper levels in maternal serum were negatively correlated with birth weight and the length of neonates. There were a number of positive correlations between maternal characteristics and birth outcomes. Mothers who consumed root vegetables frequently appeared to be protected from aluminum retention and increased body burden since their serum aluminum levels were found to be significantly lower. The findings of the current study can be used as a baseline for further research on aluminum exposure and its associated interactions and outcomes in vulnerable populations.en© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.AluminumEssential trace elementsIn utero exposureBirth outcomesMaternal serumMaternal urineSouth Africa (SA)Zinc blood levelArticle