Chan, Wai YinMtshali, Phillip SenzoGrobbelaar, AntoinetteMoolla, NaazneenMohale, ThaboLowe, MichelleDu Plessis, MorneIsmail, ArshadWeyer, Jacqueline2023-09-152023-09-152022-11-10Chan, W.Y., Mtshali, P.S., Grobbelaar, A. et al. 2022, 'Coding-complete genome sequences for two confirmed monkeypox cases in South Africa 2022', Microbiology Resource Announcements, vol. 11, no. 12, pp. 1-3. DOI : 10.1128/mra.00802-22.2576-098X10.1128/mra.00802-22http://hdl.handle.net/2263/92296DATA AVAILABILITY : The genome sequences for NICD-SVPL223 and NICD-SVPL232 were submitted to NCBI GenBank (accession numbers ON918611 and ON927248). Raw sequence data have also been deposited in NCBI (BioProject accession number PRJNA856120 and SRA accession number SRR19995508 and SRR19995509).The coding-complete genome sequences of monkeypox virus (MPXV) were obtained from skin lesion swabs from two human cases detected in South Africa in June 2022. Sequence analyses indicated that the genetic sequences of the viruses associated with these two cases were related most closely to the genetic sequences of other MPXVs reported during the 2022 multicountry outbreak and belong to the monkeypox hMPXV-1 clade (previously West Africa clade) and B.1 lineage.en© 2022 Chan et al. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license.Monkeypox virus (MPXV)Skin lesionSwabsSouth Africa (SA)SDG-03: Good health and well-beingCoding-complete genome sequences for two confirmed monkeypox cases in South Africa 2022Article