Ker, James A.Van Wyk, C.J.2008-03-152008-03-152007-11Ker, J & Van Wyk, CJ 2007, 'A case of takotsubo cardiomyopathy precipitated by lumiracoxib, a selective COX-2 inhibitor', Cardiovascular Journal of Africa, vol. 18, no. 6, pp. 383-384. [http://www.cvjsa.co.za]1015-9657http://hdl.handle.net/2263/4733Considerable controversy exists regarding the cardiovascular safety of COX-2 inhibitors, both in patients with and without established cardiovascular disease. Currently, the major focus is on thrombotic complications presenting as myocardial infarction. In this report, we present a case of takotsubo cardiomyopathy, also known as the apical ballooning syndrome, precipitated by the use of lumiracoxib. We are concerned that this might be the first case of COX-2 inhibitor-induced apical ballooning syndrome and that more may follow.244840 bytesapplication/pdfenClinics CardivCardiovascular diseaseCOX-2Takotsubo cardiomyopathyApical ballooning syndromeCardiovascular system -- DiseasesCyclooxygenase 2 -- InhibitorsTakotsubo CardiomyopathyArticle