Bigalke, R.D.2015-04-142015-04-1420141985Huismans, H 1985, 'The use of recombinant DNA technology for the development of a bluetongue virus subunit vaccine’, Onderstepoort Journal of Veterinary Research, vol. 52, no. 3, pp. 149-151.0330-2465http://hdl.handle.net/2263/44388The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.The double-stranded RNA gene coding for the surface antigen responsible for inducing neutralising antibodies has been isolated, converted to DNA, and cloned in the plasmid pBR322. So far, only plasmids containing inserts smaller than the gene have been obtained. Possible strategies for the development of a bluetongue virus subunit vaccine are discussed.en©ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Dept. of Library Services (digital).Veterinary medicineVeterinary medicine -- South AfricaArticle