Pepper, Michael Sean2019-06-252019-06-252019-092019Herd, CL 2019, Evaluating the effects of HIV-1 infection on haematopoietic stem cell colony formation, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/70293>S2019http://hdl.handle.net/2263/70293Dissertation (MSc)--University of Pretoria, 2019.The dissertation describes the production and titration of molecular clones of HIV-1B and HIV-1C primary isolates, as well as the assessment of haematopoietic stem and progenitor cell function by colony-forming unit assay towards the ultimate goal of evaluating the effects of HIV-1 infection on haematopoietic stem cell colony formation.en© 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.UCTDImmunologyHIV-1Hematopoietic stem cellsColony formationImmune systemHIV/AIDSInfectionStem cell biologyHematopoiesisImmune dysfunctionRetrovirusCD4+ T cellsImmunodeficiencyAntiretroviral therapyHealth sciences theses SDG-03SDG-03: Good health and well-beingHealth sciences theses SDG-10SDG-10: Reduced inequalitiesHealth sciences theses SDG-17SDG-17: Partnerships for the goalsDissertation