Esterhuizen, C.Cordier, Werner2025-06-132025-06-132024Esterhuizen, C. & Cordier, W. 2024, 'The misuse of analgesics and nonsteroidal anti-inflammatories in runners', SA Pharmaceutical Journal, vol. 91, no. 3, pp. 42-47. https://doi.org/10.36303/SAPJ.0361.2221-5875 (print)2220-1017 (online)10.36303/SAPJ.0361http://hdl.handle.net/2263/102831Global participation in running has continued to grow over the last decade, with millions of people running weekly, regardless of distance. These events, particularly endurance running events, require months of progressive training and load adjustment, which, combined with other factors, increase the risk of developing running-related injuries. Inflammation is a natural biological response important for healing in musculoskeletal tissue; however, it may also contribute to the unpleasant experience of pain. Runners may suffer from exercise-induced pain and inflammation, necessitating using analgesics and nonsteroidal anti-inflammatories. Unfortunately, the inappropriate use of these drugs is frequently seen in athletes, which may impact their recovery after injury or general health status. This review presents in brief the current knowledge of running-related pathology and treatment thereof, including considerations of its misuse.en© Medpharm. This article is licensed under a This article is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.5 South Africa License.AnalgesicsInflammationNonsteroidal anti-inflammatoriesPainRunningArticle