Ker, James A.Du Toit-Prinsloo, LorraineVan Heerden, Willem Francois PetrusSaayman, Gert2012-05-232012-05-232011Ker, J, Du Toit-Prinsloo, L, Van Heerden, WFP & Saayman, G 2011, 'Subendocardial fibrosis in left ventricular hypertrabeculation - cause or consequence?', Clinical Medicine Insights : Cardiology, vol. 5, pp. 13-16.1179-546810.4137/CMC.S6507http://hdl.handle.net/2263/18836Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular recesses. Recently, it has become clear that these pathological characteristics extend across a continuum with left ventricular hypertrabeculation at one end of the spectrum. The histological findings include areas of interstitial fibrosis. We present a case of left ventricular hypertrabeculation which presented as sudden infant death syndrome. Histologically areas of subendocardial fibrosis was prominent and we propose that this entity may be a hidden cause of arrhythmic death in some infants presenting as sudden infant death syndrome., with areas of subendocardial fibrosis as possible arrhythmogenic foci.en© the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited.Sudden infant death syndromeHypertrabeculationNoncompactionFibrosisArticle