Van Amstel, S.R.Reyers, FredMyburgh, ElsbePretorius, GertruidaSacks, P.Verwoerd, Daniel Wynand2013-12-092013-12-0920131994Van Amstel, SR, Reyers, F, Myburgh, E, Pretorius, G & Sacks, P 1994, 'The clinical pathology of heartwater. Ill. Changes in blood clotting, blood calcium, blood protein, haematocrit and white-cell counts in sheep with experimentally induced heartwater’, Onderstepoort Journal of Veterinary Research, vol. 61, no. 1, pp. 21-27.0330-2465http://hdl.handle.net/2263/32739The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.Studies to evaluate changes in blood clotting, blood calcium and protein, the haematocrit and white-cell counts were undertaken in seven sheep with experimentally induced heartwater. A marked decline in thrombocyte count was recorded during the acute stage of the disease. This was associated with increases in both prothrombin time (PT) and activated partial thromboplastin time (APTT) ; fibrinogen increased while there was no detectable increase in fibrinogen degradation products (FDP). At the same time total serum protein (TSP) , albumin and globulin dropped very sharply; total calcium showed a progressive drop but ionized calcium rose initially and was followed by a terminal decline. The total leucocyte count showed a terminal increase while the haematocrit dropped progressively.en© ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital).Veterinary medicineVeterinary medicine -- South AfricaHeartwater -- South AfricaArticle