Hendricks, Candice LaverneBrittain, DavidDavidson, AlanNovitzky, NicolasDu Toit, Justin RudolphThomson, JackieReynders, DavidGeel, Jennifer AnnNaidu, GitaMellet, JuanitaDurandt, ChrisnaWest, ErnaIngram, CharlotteVerburgh, EstellePepper, Michael Sean2026-02-122026Hendricks, C.L., Brittain, D., Davidson, A. et al. 2026, 'Increasing access to pediatric allogeneic hematopoietic stem cell transplantation in South Africa', Pediatric Blood & Cancer, art. e70132, doi : 10.1002/1545-5017.70132.1545-5009 (print)1545-5017 (online)10.1002/1545-5017.70132http://hdl.handle.net/2263/108131Current pediatric allogeneic hematopoietic stem cell transplantation (HSCT) services in South Africa do not meet the substantial demand in the country. The factors leading to this paucity are multifactorial, including a limited number of appropriate donors on our local registries, inadequate identification and referral of appropriate patients, long distances to travel to health facilities, socioeconomic inequality, and inadequate infrastructure and clinical expertise for the number of transplants required. We describe a model for a large HSCT unit that caters to insured and uninsured patients in order to ensure equitable access, and which is in line with the WHO health system building blocks. The scale at which transplantation will be achieved will allow for the development of local skills and expertise, which can be decentralized in the future to further improve HSCT access.en© 2026 Wiley Periodicals, Inc. This is the pre-peer reviewed version of the following article : 'Increasing access to pediatric allogeneic hematopoietic stem cell transplantation in South Africa', Pediatric Blood & Cancer, art. e70132, 2026, doi : 10.1002/1545-5017.70132. The definite version is available at : http://wileyonlinelibrary.com/journal/pbc.Bone marrow transplantEquitable accessPediatric hematopoietic stem cell transplantWHO building blocksHematopoietic stem cell transplantation (HSCT)South Africa (SA)Postprint Article