Outhoff, Kim2009-10-282009-10-282009-07Outhoff, K 2009, 'Antidepressant-induced sexual dysfunction', South African Family Practice, vol. 51, no. 4, pp. 298-302. [www.safpj.co.za]1726-426Xhttp://hdl.handle.net/2263/11617Depression and sexual dysfunction are both common in the general population. When they co-exist they have the potential to impact negatively on each other in a bidirectional manner. Medication used to treat depression may cause additional problems with the sexual response cycle; although no drug is completely innocent, serotonergic agents such as selective serotonin reuptake inhibitors reuptake inhibitors (SNRIs) are most frequently implicated in antidepressant-induced sexual dysfunction. Adherence to long-term treatment may be compromised, which may have serious consequences. Various psychological and pharmacological strategies, including the ad hoc use of sildenafil, may offer some respite.en© 2009. The Authors. Licensee: OpenJournals Publishing. This work is licensed under the Creative Commons Attribution License.DepressionSexual dysfunctionSexual disorders -- TreatmentAntidepressantsDepression, Mental -- TreatmentArticle