Van Drimmelen, G.C.Alexander, R.A.Clark, R.Louw, J.G.De Kock, V.E.2017-01-262017-01-2620161956Van Drimmelen, GC 1956, 'Strain 19 brucella vaccine. II. The preparation of freeze-dried live vaccine', Onderstepoort Journal of Veterinary Research, vol. 27, no. 2, pp. 215-225.0330-2465http://hdl.handle.net/2263/58651The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.A freeze-dried Brucella vaccine has been developed which can be issued with all the usual guarantees, e.g. 60 x 10⁹ viable organisms per dose viable for an extended period. This vaccine has been prepared in concentrated form which makes it possible to reconstitute the contents of one ampoule into a number of doses. Such a vaccine is eminently suitable for use in Southern Africa especially in the more remote areas. Concentration by means of carboxy-methyl-cellulose of the organisms grown in aerated liquid culture increased the dosage per ampoule and the survival rate after freeze-drying and during storage.en© 1956 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © 2016 University of Pretoria. Dept. of Library Services (digital).Veterinary medicineVeterinary medicine -- South AfricaArticle