Chiramba, Court KudakwasheMoller, Dalton SharlLorenz, Christian D.Chirombo, Rumbidzai RuthMason, A. JamesBester, Megan JeanGaspar, Anabella Regina Marques2024-07-252024-07-252024-03Chiramba, C.K., Möller, D.S., Lorenz, C.D. et al. 2024, 'Tryptophan end-tagging confers antifungal activity on a tick-derived peptide by triggering reactive oxygen species production', ACS Omega, vol. 9, no. 13, pp. 15556–15572, doi : 10.1021/acsomega.4c00478.2470-1343 (online)10.1021/acsomega.4c00478http://hdl.handle.net/2263/97229DATA AVAILABILITY STATEMENT : All data supporting the findings of this study are available in the figures and Supporting Information.SUPPLEMENTARY MATERIAL : Effect of antifungal agents on cell growth and viability; biofilm preventing activity of AMB, Os−C, and Os− C(W5); biofilm eradicating activity of AMB and Os− C(W5); microscopy images of cells exposed to AMB; and HPLC and MS data for Os−C and Os−C(W5).Please read abstract in the article.en© 2024 The Authors. Published by American Chemical Society. This article is licensed under CC-BY-NC-ND 4.0.BiofilmsMembranesMonomersPeptides and proteinsVesiclesAntimicrobial peptide (AMP)Tryptophan end-taggingAntifungal activityPhysiological salt environmentsSDG-03: Good health and well-beingTryptophan end-tagging confers antifungal activity on a tick-derived peptide by triggering reactive oxygen species productionArticle