Van Drimmelen, G.C.Alexander, R.A.Clark, R.Louw, J.G.De Kock, V.E.2017-01-242017-01-2420161958Van Drimmelen, GC 1958, 'Strain 19 brucella vaccine: V. Mass production in the Brucella Vortex Aerated Culture apparatus', Onderstepoort Journal of Veterinary Research, vol. 27, no. 4, pp. 539-547.0330-2465http://hdl.handle.net/2263/58608The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.The vaccine organism Brucella abortus strain 19 has been cultured in bulk in 72 litres of liquid medium aerated in a vortex system in a stainless steel culture vessel of 250 litre capacity. The lay-out and operation of the apparatus are described and results of a series of batches produced are given. The differences between various production methods are briefly presented.en© 1958 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © 2016 University of Pretoria. Dept. of Library Services (digital).Veterinary medicineVeterinary medicine -- South AfricaArticle