Niemand, JandeliBurger, Pieter BuysVerlinden, Bianca K.Reader, JanetteJoubert, Annie M.Kaiser, AnnetteLouw, Abraham IzakKirk, KiaranPhanstiel IV, OttoBirkholtz, Lyn-Marie2013-10-022013-10-022013-06Niemand, J, Burger, P, Verlinden, BK, Reader, J, Joubert, AM, Kaiser, A, Louw, AI, Kirk, K, Phanstiel IV, O & Birkholtz, LM 2013, 'Anthracene-polyamine conjugates inhibit in vitro proliferation of intraerythrocytic Plasmodium falciparum parasites', Antimicrobial Agents and Chemotherapy, vol. 57, no. 6, pp. 2874-2877.0066-4804 (print)1098-6596 (online)10.1128/AAC.00106-13http://hdl.handle.net/2263/31871Anthracene-polyamine conjugates inhibit the in vitro proliferation of the intraerythrocytic human malaria parasite, Plasmodium falciparum, with IC50 values in the nM-μM range. The compounds are taken up into the intraerythrocytic parasite where they arrest the parasite cell-cycle. Both the anthracene and polyamine components of the conjugates play a role in their antiplasmodial effect.en© 2013, American Society for Microbiology. All Rights Reserved.MalariaPlasmodium falciparumSpermidinePutrescineAnthracenePostprint Article