Maduna, Liteboho DanielLaumen, Jolein G.E.Radebe, OscarKock, Marleen M.Peters, Remco P.H.2020-03-112020-03-112019-04Maduna, L.D., Laumen, J.G.E., Radebe, O. et al. 2019, 'Failure of syndromic management due to drug-resistant Mycoplasma genitalium infection in South Africa: a case report', International Journal of STD and AIDS, vol. 30, no. 5, pp. 519-521.0956-4624 (print)1758-1052 (online)10.1177/0956462418820745http://hdl.handle.net/2263/73704We report a case of management failure of male urethritis syndrome due to macrolide-resistant Mycoplasma genitalium in South Africa. We detected mutations in 23S rRNA and one of the quinolone resistance-determining regions. This report confirms that drug-resistant M. genitalium infection can undermine the effectiveness of syndromic management in Africa.en© The Author(s) 2019Non-gonococcal urethritisBacterial diseaseUrethritis (bacterial)South Africa (SA)Mycoplasma genitaliumDrug-resistantMenPostprint Article