Charkowski, AmyBlanco, CarlosCondemine, GuyExpert, DominiqueFranz, ThierryHayes, ChristopherHugouvieux-Cotte-Pattat, NicoleSolanilla, Emilia LópezLow, DavidMoleleki, Lucy NovungayoPirhonen, MinnaPitman, AndrewPerna, NicoleReverchon, SylvieRodríguez Palenzuela, PabloSan Francisco, MichaelToth, Ian K.Tsuyumu, ShinjiVan der Waals, Jacqueline EliseVan der Wolf, JanVan Gijsegem, FrédériqueYang, Ching-HongYedidia, Iris2013-09-192013-09-192012-09Charkowski, A, ... et al 2012, 'The role of secretion systems and small molecules in soft-rot Enterobacteriaceae Pathogenicity', Annual Review of Phytopathology, vol. 50, pp. 425-449.0066-4286 (print)1545-2107 (online)10.1146/annurev-phyto-081211-173013http://hdl.handle.net/2263/31747Soft-rot Enterobacteriaceae (SRE), which belong to the genera Pectobacterium and Dickeya, consist mainly of broad host-range pathogens that cause wilt, rot, and blackleg diseases on a wide range of plants. They are found in plants, insects, soil, and water in agricultural regions worldwide. SRE encode all six known protein secretion systems present in gram-negative bacteria, and these systems are involved in attacking host plants and competing bacteria. They also produce and detect multiple types of small molecules to coordinate pathogenesis, modify the plant environment, attack competing microbes, and perhaps to attract insect vectors. This review integrates new information about the role protein secretion and detection and production of ions and small molecules play in soft-rot pathogenicity.en© 2012 by Annual Reviews. All rights reserved. This article has been accepted for publication by Annual Reviews in a revised form.Type II secretion systemType III secretion systemPlant cell wall degrading enzymesPectobacteriumDickeyaQuorum-sensingPostprint Article