Carboxy-amidated AamAP1-lys has superior conformational flexibility and accelerated killing of gram-negative bacteria

Van Wyk, Rosalind JeanetteSerem, June CheptooOosthuizen, Carel B.Semenya, DorothySerian, MirunaLorenz, Christian D.Mason, A. JamesBester, Megan JeanGaspar, Anabella Regina Marques2025-03-072025-03-072025-02Van Wyk, R.J., Serem, J.C., Oosthuizen, C.B. et al. 2025, 'Carboxy-amidated AamAP1-lys has superior conformational flexibility and accelerated killing of gram-negative bacteria', Biochemistry, vol. 64, no. 4, pp. 841-859, doi : 10.1021/acs.biochem.4c00580.0006-2960 (print)1520-4995 (online)10.1021/acs.biochem.4c00580http://hdl.handle.net/2263/101390Please read abstract in the article.en© 2025 The Authors. Published by American Chemical Society. This publication is licensed under CC-BY 4.0.BacteriaBiofilmsMembranesOrganic reactionsPeptides and proteinsAntimicrobial peptide (AMP)C-terminal amidationSDG-03: Good health and well-beingCarboxy-amidated AamAP1-lys has superior conformational flexibility and accelerated killing of gram-negative bacteriaArticle