Eimontas, JonasGegieckaitė, GodaAsaciova, IrenaSticinskaitė, NikolArcimaviciute, LivijaSavickaite, DovileVaitiekunaite‑Zubriakoviene, DonataGans, JenniferBeukes, Eldre W.Manchaiah, VinayaAndersson, GerhardLesinskas, Eugenijus2024-01-112024-01-112023-04-12Eimontas, J., Gegieckaitė, G., Asačiova, I. et al. Internet-delivered cognitive behavioral therapy for tinnitus compared to Internet-delivered mindfulness for tinnitus: a study protocol of a randomized controlled trial. Trials 24, 269 (2023). https://doi.org/10.1186/s13063-023-07299-9.1745-6215 (online)10.1186/s13063-023-07299-9http://hdl.handle.net/2263/93911AVAILABILITY OF DATA AND MATERIALS : After the publication of trial results, a de-identified dataset will be available from the PI upon a reasonable request.BACKGROUND : Tinnitus affects around 15% of the population and can be a debilitating condition for a sizeable part of them. However, effective evidence-based treatments are scarce. One recommended treatment for tinnitus is cognitive behavioral therapy which has been found to be effective when delivered online. However, more treatments including mindfulness-based interventions have been studied recently in an attempt to facilitate the availability of effective treatments. There are promising findings showing great effects in reducing tinnitus-induced distress and some evidence about the efficacy of such intervention delivered online. However, there is a lack of evidence on how these two treatments compare against one another. Therefore, the aim of this study will be to compare Internet-delivered cognitive behavioral therapy for tinnitus against an Internet-delivered mindfulness-based tinnitus stress reduction intervention in a three-armed randomized controlled trial with a waiting list control condition. METHODS : This study will be a randomized controlled trial seeking to recruit Lithuanian-speaking individuals suffering from chronic tinnitus. The self-report measure Tinnitus Handicap Inventory will be used. Self-referred participants will be randomized into one of three study arms: Internet-delivered cognitive behavioral therapy, Internet-delivered mindfulness- based tinnitus stress reduction intervention, or a waiting-list control group. Post-treatment measures will be taken at the end of the 8-week-long intervention (or waiting). Long-term efficacy will be measured 3 and 12 months post-treatment. DISCUSSION : Internet-delivered interventions offer a range of benefits for delivering evidence-based treatments. This is the first randomized controlled trial to directly compare Internet-delivered CBT and MBTSR for tinnitus in a noninferiority trial. TRIAL REGISTRATION : ClinicalTrials.gov NCT05705323. Registered on January 30, 2023.en© The Author(s) 2023. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License.Internet-delivered interventionsTinnitusMindfulnessTinnitus distressCognitive behavioral therapy (CBT)Internet-based CBT intervention for tinnitus (ICBT)Mindfulness based Tinnitus stress reduction (MBTSR)Internet-delivered iMBTSRRandomized controlled trial (RCT)SDG-03: Good health and well-beingArticle