Barrowman, P.R.Coetzer, J.A.W.Kellerman, T.S.De Vos, A.J.Bigalke, R.D.Cameron, Colin McKenzieGilchrist, Frances M.C.Morren, A.J.Verster, Anna J.M.Verwoerd, Daniel WynandWalker, Jane B.De Kock, V.E.2016-07-072016-07-0720161978De Vos, AJ, Barrowman, PR, Coetzer, JAW & Kellerman, TS 1978, 'Amicarbalide : A therapeutic agent for anaplasmosis.’ Onderstepoort Journal of Veterinary Research, vol. 45, no. 3, pp. 203-208.0330-2465http://hdl.handle.net/2263/54120The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.When administered subcutaneously in 2 equal daily doses at a total dosage rate of 20 mg/kg, amicarbalide was found to be an effective agent for controlling acute infections of Anaplasma marginate and A. centrale in intact and splenectomized cattle. Attempts to sterilize patent and latent Anaplasma infections, however, were unsuccessful. At total dosage rates of 40 mg/kg and higher, amicarbalide exhibited potent hepato- and nephrotoxic tendencies.en© 1978 ARC – Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © 2016 University of Pretoria. Department of Library Services (digital).Veterinary medicineVeterinary medicine -- South AfricaArticle