Lane, Emily P.Brettschneider, HeleneCaldwell, PeterOosthuizen, AlmeroDalton, Desire L.Du Plessis, LizaSteyl, Johan Christian AbrahamKotze, Antoinette2016-07-132016-07-132016-06-09Lane, E.P., Brettschneider, H., Caldwell, P., Oosthuizen, A., Dalton, D.L., Du Plessis, L. et al., 2016, ‘Feline panleukopaenia virus in captive non-domestic felids in South Africa’, Onderstepoort Journal of Veterinary Research 83(1), a1099. http://dx.DOI. org/ 10.4102/ojvr.v83i1.1099.0030-2465 (print)2219-0635 (online)10.4102/ojvr.v83i1.1099http://hdl.handle.net/2263/55524An outbreak of feline panleukopaenia virus (FPLV) infection was diagnosed by pathology, electron microscopy and polymerase chain reaction (PCR) in vaccinated captive-bred subadult cheetahs in South Africa. Subsequent to this disease outbreak, 12 cases of FPLV diagnosed on histology were confirmed by PCR in captive African black-footed cat, caracal, cheetah, lion, ocelot and serval. Phylogenetic analyses of the viral capsid protein gene on PCR-positive samples, vaccine and National Center for Biotechnology Information (NCBI) reference strains identified a previously unknown strain of FPLV, present since at least 2006, that differs from both the inactivated and the modified live vaccine strains. A previously described South African strain from domestic cats and cheetahs was identified in a serval. Surveys of FPLV strains in South African felids are needed to determine the geographical and host species distribution of this virus. Since non-domestic species may be reservoirs of parvoviruses, and since these viruses readily change host specificity, the risks of FPLV transmission between captive-bred and free-ranging carnivores and domestic cats and dogs warrant further research.en© 2016. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.Feline panleukopaenia virus (FPLV)Polymerase chain reaction (PCR)National Center for Biotechnology Information (NCBI)South AfricaArticle