Mahomed, Shenaaz IsmailVoyi, K.V.V. (Kuku)Aneck-Hahn, Natalie HildegardDe Jager, Christiaan2008-10-172008-10-172008Mahomed, SI, Voyi, KVV, Aneck-Hahn, NH & De Jager, C 2008,'Oestrogenicity and chemical target analysis of water from small-sized industries in Pretoria, South Africa’, Water SA, vol. 34, no. 3, pp. 357-363.[http://www.wrc.org.za/publications_watersa.htm]03784738http://hdl.handle.net/2263/7591Increasing concern about endocrine disrupting chemicals (EDCs) and their effects on humans, animals and the environment resulted in this study being conducted. Water from 7 sites in the Pretoria West area (South Africa), with significant numbers of small-sized industries, was screened for oestrogenicity, using the Recombinant Yeast Cell Bioassay (RCBA). Target chemical analyses were carried out to establish the presence of EDCs, including p-nonylphenol (p-NP), bisphenol A (BPA), phthalate esters, polychlorinated biphenyls (PCBs) and various organochlorine pesticides, including dichlorodiphenyltrichloroethane (DDT). p-NP, PCBs and organochlorine pesticides were detected using LECO Pegasus II MSTOF and BPA and phthalates were detected using the GC-MS method. Oestrogenic activity was detected in all the samples collected from these sites. Lindane, an organochlorine pesticide, was detected at one site. p-NP, PCBs and phthalate esters were detected at some of the other sites. Small-size industries were found to contribute to EDC pollution of water in the Pretoria West area.enWater Research CouncilOestrogenicityEndocrine disrupting chemicals (EDCs)P-nonylphenol (p-NP)Polychlorinated biphenyls (PCBs)Bisphenol A (BPA)Phthalate estersOrganochlorine pesticidesDichlorodiphenyltrichloroethane (DDT)LindaneEndocrine disrupting chemicals in water -- Gauteng (South Africa)Bisphenol APhthalate estersDDT (Insecticide)Small businessLindaneArticle