Ally, Mahmood Moosa Tar MahomedHodkinson, Bridget2014-08-222014-08-222014-05Ally, M & Hodkinson, B 2014, 'Rheumatoid arthritis', South African Family Practice, vol. 56, no. 3, pp. 166-171.2078-6190 (print)2078-6204 (online)10.1080/20786204.2014.932547http://hdl.handle.net/2263/41555Immune-mediated inflammatory disorders include a clinically diverse group of conditions that share similar pathogenic mechanisms. Conditions such as rheumatoid arthritis (RA), psoriasis, spondyloarthropathy, inflammatory bowel disease and connective-tissue disease are characterised by immune dysregulation and chronic inflammation. This review will focus on immunopathogenic mechanisms, aspects of early disease, co-morbidity and therapy in RA.en© 2014 http://hdl.handle.net/2263/41556. Open Access article distributed under the terms of the Creative Commons License [CC BY-NC-ND 4.0].ImmuneInflammatoryTherapyRheumatoid arthritis (RA)Article