Coertse, JessicaGeldenhuys, MarikeLe Roux, KevinMarkotter, Wanda2022-09-082022-09-082021-03-29Coertse, J.; Geldenhuys, M.; le Roux, K.; Markotter, W. Lagos Bat Virus, an Under-Reported Rabies-Related Lyssavirus. Viruses 2021, 13, 576. https://doi.org/10.3390/v13040576.1999-4915 (online)10.3390/v13040576https://repository.up.ac.za/handle/2263/87127Lagos bat virus (LBV), one of the 17 accepted viral species of the Lyssavirus genus, was the first rabies-related virus described in 1956. This virus is endemic to the African continent and is rarely encountered. There are currently four lineages, although the observed genetic diversity exceeds existing lyssavirus species demarcation criteria. Several exposures to rabid bats infected with LBV have been reported; however, no known human cases have been reported to date. This review provides the history of LBV and summarizes previous knowledge as well as new detections. Genetic diversity, pathogenesis and prevention are re-evaluated and discussed.en© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).LyssavirusBatsRabiesAfricaLagos bat lyssavirus (LBV)South Africa (SA)Article