Botha, C.J. (Christoffel Jacobus)2014-05-062014-05-062013-11-18Botha, C.J., 2013, ‘Krimpsiekte in South Africa: Historical perspectives’, Journal of the South African Veterinary Association 84(1), Art. #1059, 5 pages. http://dx.DOI.org/ 10.4102/jsava.v84i1.10590038-223X (print)2225-6253 (online)10.4102/jsava.v84i1.10597006558662O-5991-2014http://hdl.handle.net/2263/39710Krimpsiekte, also known as cotyledonosis or nenta in sheep and goats, has been recognised as a disease entity since 1775. However, it was only in 1891 that Veterinary Surgeon Soga reproduced the condition by dosing Cotyledon (= Tylecodon) ventricosus leaves to goats. Professor MacOwan, a botanist, confirmed the identity of these nenta plants. From a South African veterinary toxicological point of view the date 1891 is of considerable historical significance as this was the first time that a plant was experimentally demonstrated to be toxic to livestock in South Africa. A chronological account of the history of krimpsiekte research is provided.en© 2013. The Authors. Licensee: AOSIS OpenJournals. This work is licensed under the Creative Commons Attribution License.KrimpsiekteSouth AfricaSheepVeterinary surgeonsCotyledonosisNentaVeterinary medicine -- ResearchVeterinary medicine -- History -- South AfricaGoatsArticle